All news 19.03.2019

NEW HYBRID IMAGING METHOD WITH PROSTATE CARCINOMA PATIENTS

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This innovative examination optimizes the treatment plan, saves expensive procedures and many efforts for the patient

In end of March 2019 the Nuclear Medicine Clinic at Acibadem City Clinic – Oncology Center started a hybrid imaging diagnostic procedure for prostate cancer /PC/ with new radiopharmaceutical in line with the latest world standards. The new examination helps the physicians to visualize the relapse /tumour tissues that have newly appeared after the radical treatment/ in prostate carcinoma patients.

The end effect of the innovative diagnostics is a change of the therapy of up to 54% of the patients and prescription of personalized treatment. 10% of the patient with early stages - their treatment plan develops into a radical one and the patient is expected to recover fully. The optimization of the treatment plan saves resources of other expensive invasive and non-invasive examinations and therapies.

Currently, magnetic-resonance imaging and contrast computer tomography is used for PC staging to visualize the relapses but they are not always accurate enough at low levels of the tumour marker. The implementation of the new radiopharmaceutical 68Ga-PSMA in combination with molecular imaging and CT gives the opportunity to the physicians to visualize the pathological changes at an earlier stage and with low values of the tumour marker.

Research is being carried out to use 68Ga-PSMA PET-CT in the relapse of brain tumours and primary hepatocellular carcinoma. The initial comparative data of this radiopharmaceutical with 68Ga-PSMA PET-CT shows its lower sensitivity when detecting metastasis in lymph nodes of sizes less than 10 mm; its implementation in intraopreative detection with a gamma probe. The results ought to be summarized based on a bigger number of patients.

The Nuclear Medicine Department at Acibadem City Clinic- Oncology Center has the most sensitive PET-CT with 5-ring sensor giving the unique opportunity to examine cancer patients for a shorter period of time and with smaller quantity of applied radioactive substance. So, a series of inconvenience of a long-lasting examination are saved in this manner and the radiation loading reduces by about 30%.